Recombinant Podoplanin antibody

Catalog No. ABIN7861930

The Rabbit Monoclonal anti-Podoplanin antibody (Clone PDPN-8950R) (ABIN7861930) specifically detects Podoplanin in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Podoplanin antibody (ABIN7861930)

Target: Podoplanin (PDPN)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: PDPN-8950R

Product Details anti-Podoplanin Antibody

Purpose: Recombinant Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody

Specificity: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium 79oΩas well as lymphoangiomas, 79oΩKaposi sarcomas, 79oΩand in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human PDPN protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background:

Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8,

cervical or lung carcinoma tissues.|Human tonsil

Molecular Weight: 17kDa

Gene ID: 10630, 468675

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport