Recombinant Stathmin 1 antibody

Catalog No. ABIN7864113

The Rabbit Monoclonal anti-Stathmin 1 antibody (Clone STMN1-8001R) (ABIN7864113) specifically detects Stathmin 1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Stathmin 1 antibody (ABIN7864113)

Target: Stathmin 1 (STMN1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: STMN1-8001R

Product Details anti-Stathmin 1 Antibody

Purpose: Recombinant Stathmin 1 / STMN1 Antibody

Specificity: Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human STMN1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background:

C1orf215, Lag, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin1, STMN 1

Human brain or melanoma tissue.

Molecular Weight: 19kDa

Gene ID: 3925, 209983

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics