Stathmin 1 antibody

Catalog No. ABIN7862121

The Mouse Monoclonal anti-Stathmin 1 antibody is suitable to detect Stathmin 1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for Stathmin 1 antibody (ABIN7862121)

Target: Stathmin 1 (STMN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: STMN1-8012

Product Details anti-Stathmin 1 Antibody

Purpose: Stathmin 1 / STMN1 Antibody

Specificity: Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human STMN1 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background:

C1orf215, Lag, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin1, STMN 1

Human brain, Spleen or melanoma tissue.

Molecular Weight: 19kDa

Gene ID: 3925, 209983

Pathways: MAPK Signaling, Microtubule Dynamics