ZMYM3 antibody
Quick Overview for ZMYM3 antibody (ABIN7862290)
Target
See all ZMYM3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- ZMYM3 Antibody
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Specificity
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZMYM3 (zinc finger MYM-type protein 3), also known as ZNF261 (zinc finger protein 261), XFIM, DXS6673E or MYM, is a 1,370 amino acid nuclear protein that contains nine MYM-type zinc fingers. Expressed in a variety of tissues, including heart, muscle and brain, ZMYM3 is thought to function as part of a histone deacetylase-containing complex that contains other proteins, such as HDAC1 and HDAC2, and may play a role in gene silencing through the modification of chromatin structure. Defects in the gene encoding ZMYM3 that lead to chromosomal translocations may be a cause of X-linked mental retardation. Two isoforms of ZMYM3 exist due to alternative splicing events.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant full-length human ZMYM3 protein
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Isotype
- IgG2a
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Expiry Date
- 24 months
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- ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
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Alternative Name
- ZMYM3
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Background
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DXS6673E, KIAA0385, MYM, XFIM, ZFP261, Zinc finger MYM type 3, Zinc finger MYM type protein 3, Zinc finger MYM-type protein 3, Zinc finger protein 261, ZNF198L2, ZNF261
HeLa or Raji cells. Ubiquitious nuclear expression.
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Molecular Weight
- 152kDa
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Gene ID
- 9203, 522684
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UniProt
- Q14202
Target
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