Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF804A (zinc-finger protein 804A) is a 1,209 amino acid protein that contains one C2H2-type zinc finger. ZNF804A interacts with Ataxin-1, a protein that is involved in RNA metabolism. The gene encoding ZNF804A maps to human chromosome 2, which consists of 237 million bases and encodes over 1,400 genes, making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2.
Purification
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
200 μg/mL
Buffer
Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Target
ZNF804A
(Zinc Finger Protein 804A (ZNF804A))
Alternative Name
ZNF804A
Background
HeLa cells. Human brain, lymph node, thyroid or small intestine.