The Mouse Monoclonal anti-ZNF804A antibody (Clone ZNF804A-8945) (ABIN7879366) specifically detects ZNF804A in IHC (p).
The antibody is reactive with Human samples.
Optimal dilution of the ZNF804A antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the ZNF804A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
ZNF804A
(Zinc Finger Protein 804A (ZNF804A))
Alternative Name
ZNF804A
Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF804A (zinc-finger protein 804A) is a 1,209 amino acid protein that contains one C2H2-type zinc finger. ZNF804A interacts with Ataxin-1, a protein that is involved in RNA metabolism. The gene encoding ZNF804A maps to human chromosome 2, which consists of 237 million bases and encodes over 1,400 genes, making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2.