Neurofilament antibody

Catalog No. ABIN7863696

This Mouse Monoclonal antibody specifically detects Neurofilament in FACS, IHC and IF. It exhibits reactivity toward Human, Rat, Chicken, Pig and Mouse.

Quick Overview for Neurofilament antibody (ABIN7863696)

Target: Neurofilament

Reactivity: Human, Rat, Chicken, Pig, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neurofilament antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: NF421-NFL-736

Product Details anti-Neurofilament Antibody

Purpose: Neurofilament (H+L) (Neuronal Marker) Antibody

Specificity: This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate.

Immunogen: Recombinant human neurofilament protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Neurofilament

Target: Neurofilament

Background:

NEFH, Neurofilament H, Neurofilament Heavy Polypeptide 200 kDa, Neurofilament Triplet H Protein, NF-H, NF200. 68 kDa neurofilament protein, Light molecular weight neurofilament protein, NEFL, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF-L, Neurofilament triplet L protein, NF-L, NF68

HEK293 cells. Human brain or neuroblastoma.

Molecular Weight: 200kDa & 68kDa

Gene ID: 4744, 198760

UniProt: P12036