Hepatocyte Specific Antigen antibody

Catalog No. ABIN7862452

The Mouse Monoclonal anti-Hepatocyte Specific Antigen antibody (Clone MSVA-OCE5) (ABIN7862452) specifically detects Hepatocyte Specific Antigen in IHC. The antibody is reactive with Human samples.

Quick Overview for Hepatocyte Specific Antigen antibody (ABIN7862452)

Target: Hepatocyte Specific Antigen (HepPar-1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hepatocyte Specific Antigen antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: MSVA-OCE5

Product Details anti-Hepatocyte Specific Antigen Antibody

Purpose: Hepatocyte Specific Antigen (Hepatocellular Marker) Antibody

Specificity: Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or HepPar1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC's occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Purification: Ab purified from Bioreactor Concentrate by Protein G.

Immunogen: Extract of a formalin-fixed, rejected-allograft of a human liver

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Hepatocyte Specific Antigen

Target: Hepatocyte Specific Antigen (HepPar-1)

Alternative Name: Hepatocyte Specific Antigen

Background:

Not Known

Liver: Virtually all hepatocytes should show an at least moderate granular cytoplasmic staining.