CHRNA6 antibody

Catalog No. ABIN7862516

This Rabbit Polyclonal antibody specifically detects CHRNA6 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHRNA6 antibody (ABIN7862516)

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHRNA6 Antibody

Purpose: Rabbit Anti-ACHA6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ACHA6 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ACHA6 protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHRNA6

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Alternative Name: ACHA6

Background: Neuronal acetylcholine receptor subunit alpha-6CHRNA6 (Cholinergic Receptor Nicotinic Alpha 6 Subunit) is a Protein Coding gene. Diseases associated with CHRNA6 include Autosomal Dominant Nocturnal Frontal Lobe Epilepsy and Alcohol Dependence. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Acetylcholine Binding And Downstream Events. CHRNA6 encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine.

Molecular Weight: 54kD

Gene ID: 8973

UniProt: Q15825