TBXA2R antibody

Catalog No. ABIN7862561

This Rabbit Polyclonal antibody specifically detects TBXA2R in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TBXA2R antibody (ABIN7862561)

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXA2R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TBXA2R Antibody

Purpose: Rabbit Anti-TA2R Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TA2R protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TA2R protein at AA range: 230-310

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TBXA2R

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Alternative Name: TA2R

Background: Thromboxane A2 receptor, TXA2-R, Prostanoid TP receptorReceptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.

Molecular Weight: 37kD

Gene ID: 6915

UniProt: P21731