Syndecan 1 antibody

Catalog No. ABIN7865740

The Mouse Monoclonal anti-Syndecan 1 antibody (Clone IHC138) (ABIN7865740) specifically detects Syndecan 1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Syndecan 1 antibody (ABIN7865740)

Target: Syndecan 1 (SDC1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Syndecan 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC138

Product Details anti-Syndecan 1 Antibody

Purpose: anti-CD138 mouse monoclonal, IHC138, purified

Purification: affinity chromatography

Immunogen: Recombinant Human CD138

Isotype: IgG1 kappa

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for Syndecan 1

Target: Syndecan 1 (SDC1)

Alternative Name: CD138

Background: Cluster of Differentiation 138 (CD138), also known as Syndecan-1, is a trans- membrane glycoprotein present on the surface of B-cells during late stage differentiation. Anti-CD138 is used to differentiate marginal zone lymphoma from lymphoplasmacytic lymphoma. ALK+ Large B-Cell Lymphoma (LBCL) commonly stains positively for CD138, but not for CD20 and CD79a. Anti-CD138 reacts positively with HHV8-associated primary effusion lymphoma that lacks B-cell markers. CD138 is also a useful marker for identifying and enumerating benign, reactive, or malignant plasma cells from the bone marrow biopsy samples.

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism