CD56 antibody

Catalog No. ABIN7866124

This Mouse Monoclonal antibody specifically detects CD56 in FACS, IHC, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CD56 antibody (ABIN7866124)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: C5-9

Product Details anti-CD56 Antibody

Purpose: Mouse anti Human CD56 Prediluted

Characteristics: NCAM / CD56, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM can be found in central and peripheral nerve cells, neuroendocrine tissues and at the surface of NK-cells. Also, NCAM is present in malignancies derived from these tissues and cells.

Purification: Protein A/G Chromatography

Immunogen: Extract from KG1a cell line.,Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c F1 mice immunized with KG1a cell line.

Isotype: IgG2b

Application Details

Application Notes: Product provided in dropper bottle and should be used as provided. Use 2-3 drops per section or sufficient solution to cover section.

Restrictions: For Research Use only

Handling

Buffer: Prediluted monoclonal antibody C5.9 in PBS containing 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Product should be stored at 4-8°C. DO NOT FREEZE

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: CD56

Background: CD56, NCAM, Neural Cell Adhesion Molecule

UniProt: P13591