IL-10 antibody

Catalog No. ABIN7866177

The Rat Monoclonal anti-IL-10 antibody (Clone R-625) (ABIN7866177) specifically detects IL-10 in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for IL-10 antibody (ABIN7866177)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: R-625

Product Details anti-IL-10 Antibody

Purpose: Rat anti Human IL-10

Characteristics: IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.

Purification: Protein A/G Chromatography

Isotype: IgG1

Application Details

Application Notes: Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Target Details for IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Alternative Name: IL-10

Background: Rat anti human Interleukin-4, IL-4, unconjugated

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints