Recombinant Asialoglycoprotein Receptor 1 antibody (PE)

Catalog No. ABIN7867096

The PE-conjugated Rabbit Chimeric anti-Asialoglycoprotein Receptor 1 antibody (Clone DMC688) (ABIN7867096) specifically detects Asialoglycoprotein Receptor 1 in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant Asialoglycoprotein Receptor 1 antibody (PE) (ABIN7867096)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This Asialoglycoprotein Receptor 1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC688

Product Details anti-Asialoglycoprotein Receptor 1 Antibody (PE)

Purpose: PE-conjugated Anti-ASGR1 antibody(DMC688), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1

Background:

Synonyms: ASGPR, ASGPR1, CLEC4H1, HL-1

Target Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

UniProt: P07306

Pathways: Thyroid Hormone Synthesis