GRPR antibody

Catalog No. ABIN7867282

The Rabbit Monoclonal anti-GRPR antibody (Clone 3B12) (ABIN7867282) specifically detects GRPR in FACS. The antibody is reactive with Human samples.

Quick Overview for GRPR antibody (ABIN7867282)

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GRPR antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 3B12

Product Details anti-GRPR Antibody

Purpose: Anti-GRPR antibody(3B12), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Handling Advice: Avoid repeated freezing and thawing,After reconstitution, if not intended for use within a month, aliquot and store at -80 °C

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Expiry Date: 12 months

Target Details for GRPR

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Alternative Name: GRPR

Background:

Synonyms: BB2,BB2R,BRS2

Target Background: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]

UniProt: P30550