Recombinant IFNA2 antibody (PE)

Catalog No. ABIN7867330

The PE-conjugated Rabbit Chimeric anti-IFNA2 antibody (Clone 1B7) (ABIN7867330) specifically detects IFNA2 in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant IFNA2 antibody (PE) (ABIN7867330)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This IFNA2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 1B7

Product Details anti-IFNA2 Antibody (PE)

Purpose: PE-conjugated Anti-IFNA2 antibody(1B7), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Alternative Name: IFNA2

Background:

Synonyms: IFNA, IFNA2B, leIF A, IFN-alphaA, IFN-alpha-2

Target Background: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. [provided by RefSeq, Aug 2020]

UniProt: P01563

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C