LAIR1 antibody

Catalog No. ABIN7867355

This Rabbit Monoclonal antibody specifically detects LAIR1 in FACS. It exhibits reactivity toward Human.

Quick Overview for LAIR1 antibody (ABIN7867355)

Target: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LAIR1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1A2

Product Details anti-LAIR1 Antibody

Purpose: Anti-LAIR1 antibody(1A2), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Handling Advice: Avoid repeated freezing and thawing,After reconstitution, if not intended for use within a month, aliquot and store at -80 °C

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for LAIR1

Target: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Alternative Name: LAIR1

Background:

Synonyms: CD305,LAIR-1

Target Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt: Q6GTX8