MICB antibody (PE)

Catalog No. ABIN7867370

This Rabbit Monoclonal antibody specifically detects MICB in FACS. It exhibits reactivity toward Human.

Quick Overview for MICB antibody (PE) (ABIN7867370)

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MICB antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM168

Product Details anti-MICB Antibody (PE)

Purpose: PE-conjugated Anti-MICB antibody(DM168), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Alternative Name: MICB

Background:

Synonyms: MIC-B, PERB11.2

Target Background: This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response