CD43 antibody (PE)

Catalog No. ABIN7867432

The PE-conjugated Rabbit Monoclonal anti-CD43 antibody (Clone DM211) (ABIN7867432) specifically detects CD43 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD43 antibody (PE) (ABIN7867432)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD43 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM211

Product Details anti-CD43 Antibody (PE)

Purpose: PE-conjugated Anti-CD43 antibody(DM211), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background:

Synonyms: CD43, GALGP, GPL115, LSN

Target Background: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity