Recombinant TREM2 antibody (PE)

Catalog No. ABIN7867465

The PE-conjugated Rabbit Chimeric anti-TREM2 antibody (Clone DMC223) (ABIN7867465) specifically detects TREM2 in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant TREM2 antibody (PE) (ABIN7867465)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This TREM2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC223

Product Details anti-TREM2 Antibody (PE)

Purpose: PE-conjugated Anti-TREM2 antibody(DMC223), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2

Background:

Synonyms: PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c

Target Background: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9NZC2