Recombinant YAP1 antibody (PE)

Catalog No. ABIN7867487

This Rabbit Chimeric antibody specifically detects YAP1 in FACS. It exhibits reactivity toward Human.

Quick Overview for Recombinant YAP1 antibody (PE) (ABIN7867487)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This YAP1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC495

Product Details anti-YAP1 Antibody (PE)

Purpose: PE-conjugated Anti-YAP1 antibody(DMC495), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background:

Synonyms: COB1, YAP, YAP2, YAP65, YKI

Target Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha