CD55 antibody (AA 1-100)

Catalog No. ABIN7867830

The Mouse Monoclonal anti-CD55 antibody is suitable to detect CD55 in samples from Human. It has been validated for WB.

Quick Overview for CD55 antibody (AA 1-100) (ABIN7867830)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: CD55-6795

Product Details anti-CD55 Antibody

Binding Specificity: AA 1-100

Purpose: CD55 Antibody

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 1-100 was used as the immunogen for the CD55 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD55 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD55 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55

Background: Recognizes a single chain glycoprotein of 70 kDa, identified as CD55/DAF. It is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus.

UniProt: P08174

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity