alpha Tubulin antibody (AA 1-115)

Catalog No. ABIN7867967

This Mouse Monoclonal antibody specifically detects alpha Tubulin in IHC (p). It exhibits reactivity toward Human.

Quick Overview for alpha Tubulin antibody (AA 1-115) (ABIN7867967)

Target: alpha Tubulin (TUBA1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Tubulin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TUBA-3038

Product Details anti-alpha Tubulin Antibody

Binding Specificity: AA 1-115

Purpose: Alpha Tubulin Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 1-115 from the human protein was used as the immunogen for the Alpha Tubulin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Alpha Tubulin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Alpha Tubulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for alpha Tubulin

Target: alpha Tubulin (TUBA1)

Alternative Name: Alpha Tubulin

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. This MAb recognizes an epitope of alpha-tubulin. The alpha-tubulin is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants - tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in C-terminal structural domain

UniProt: P68363

Pathways: Microtubule Dynamics