Recombinant ATG5 antibody (AA 1-119)

Catalog No. ABIN7867994

This Mouse Monoclonal antibody specifically detects ATG5 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant ATG5 antibody (AA 1-119) (ABIN7867994)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RATG5-2553

Product Details anti-ATG5 Antibody

Binding Specificity: AA 1-119

Purpose: Recombinant ATG5 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 1-119) was used as the immunogen for the ATG5 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant ATG5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant ATG5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Alternative Name: ATG5

Background: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy, a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy