ATG5 antibody (AA 1-119)

Catalog No. ABIN7867995

The Mouse Monoclonal anti-ATG5 antibody is suitable to detect ATG5 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for ATG5 antibody (AA 1-119) (ABIN7867995)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: ATG5-2553

Product Details anti-ATG5 Antibody

Binding Specificity: AA 1-119

Purpose: ATG5 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 1-119) was used as the immunogen for the ATG5 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the ATG5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the ATG5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Alternative Name: ATG5

Background: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy, a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy