FABP1 antibody (AA 1-127)

Catalog No. ABIN7868040

The Mouse Monoclonal anti-FABP1 antibody is suitable to detect FABP1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for FABP1 antibody (AA 1-127) (ABIN7868040)

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FABP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: FABP1-3487

Product Details anti-FABP1 Antibody

Binding Specificity: AA 1-127

Purpose: FABP1 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 1-127 from the human protein was used as the immunogen for the FABP1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the FABP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the FABP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FABP1

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Alternative Name: FABP1

Background: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

UniProt: P07148

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha