FABP1 antibody (AA 1-127)

Catalog No. ABIN7868045

This Mouse Monoclonal antibody specifically detects FABP1 in WB. It exhibits reactivity toward Human.

Quick Overview for FABP1 antibody (AA 1-127) (ABIN7868045)

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FABP1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: FABP1-4518

Product Details anti-FABP1 Antibody

Binding Specificity: AA 1-127

Purpose: FABP1 Antibody

Purification: Protein G affinity

Immunogen: A human partial recombinant protein (from within amino acids 1-127 was used as the immunogen for the FABP1 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the FABP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FABP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FABP1

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Alternative Name: FABP1

Background: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

UniProt: P07148

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha