JAZF1 antibody (AA 1-130)

Catalog No. ABIN7868080

The Mouse Monoclonal anti-JAZF1 antibody (Clone PCRP-JAZF1-1C2) (ABIN7868080) specifically detects JAZF1 in WB, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for JAZF1 antibody (AA 1-130) (ABIN7868080)

Target: JAZF1 (JAZF Zinc Finger 1 (JAZF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAZF1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PCRP-JAZF1-1C2

Product Details anti-JAZF1 Antibody

Binding Specificity: AA 1-130

Purpose: JAZF1 Antibody

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 1-130 was used as the immunogen for the JAZF1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the JAZF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the JAZF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for JAZF1

Target: JAZF1 (JAZF Zinc Finger 1 (JAZF1))

Alternative Name: JAZF1

Background: JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.

UniProt: Q86VZ6