Retinoid X Receptor alpha antibody (AA 1-133)

Catalog No. ABIN7868102

This Rabbit Polyclonal antibody specifically detects Retinoid X Receptor alpha in WB, ELISA and FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for Retinoid X Receptor alpha antibody (AA 1-133) (ABIN7868102)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoid X Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-Retinoid X Receptor alpha Antibody

Binding Specificity: AA 1-133

Purpose: RXR alpha Antibody / Retinoid X receptor alpha

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-H133) was used as the immunogen for the RXR alpha antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RXR alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RXR alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Alternative Name: RXR alpha

Background: Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear receptor that in humans is encoded by the RXRA gene. Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C