OLIG2 antibody (AA 1-141)

Catalog No. ABIN7868143

The Mouse Monoclonal anti-OLIG2 antibody (Clone OLIG2-2400) (ABIN7868143) specifically detects OLIG2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for OLIG2 antibody (AA 1-141) (ABIN7868143)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OLIG2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: OLIG2-2400

Product Details anti-OLIG2 Antibody

Binding Specificity: AA 1-141

Purpose: OLIG2 Antibody (azide and preservative free)

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-141 from the human protein was used as the immunogen for this OLIG2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the OLIG2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the OLIG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Alternative Name: OLIG2

Background: Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).

UniProt: Q13516