NDUFA13 antibody (AA 1-144)

Catalog No. ABIN7868157

The Rabbit Polyclonal anti-NDUFA13 antibody is suitable to detect NDUFA13 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for NDUFA13 antibody (AA 1-144) (ABIN7868157)

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-NDUFA13 Antibody

Binding Specificity: AA 1-144

Purpose: GRIM19 Antibody / NDUFA13

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-T144) was used as the immunogen for the GRIM19 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GRIM19 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GRIM19 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: GRIM19

Background: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 is an enzyme that in humans is encoded by the NDUFA13 gene. This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling