Recombinant Iba1 antibody (AA 1-146)

Catalog No. ABIN7868161

The Rabbit Monoclonal anti-Iba1 antibody (Clone AIF1-8970R) (ABIN7868161) specifically detects Iba1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Iba1 antibody (AA 1-146) (ABIN7868161)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Iba1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AIF1-8970R

Product Details anti-Iba1 Antibody

Binding Specificity: AA 1-146

Purpose: Allograft inflammatory factor 1 Antibody / AIF1 / IBA1

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-146) from the human protein was used as the immunogen for the Allograft inflammatory factor 1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Allograft inflammatory factor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Allograft inflammatory factor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: Allograft inflammatory factor 1

Background: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

UniProt: P55008

Pathways: Smooth Muscle Cell Migration