Recombinant Stathmin 1 antibody (AA 1-148)

Catalog No. ABIN7868178

The Rabbit Monoclonal anti-Stathmin 1 antibody is suitable to detect Stathmin 1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant Stathmin 1 antibody (AA 1-148) (ABIN7868178)

Target: Stathmin 1 (STMN1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: STMN1-9227R

Product Details anti-Stathmin 1 Antibody

Binding Specificity: AA 1-148

Purpose: Recombinant Stathmin 1 Antibody / STMN1

Purification: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 1-148) of human STMN1 protein was used as the immunogen for the recombinant Stathmin 1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Stathmin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Stathmin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background: Stathmin 1 (Oncoprotein 18, STM1, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of the protein are observed, and it is expressed as two different isoforms. Stathmin 1 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. It is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics