PEG3 antibody (AA 1-1548)

Catalog No. ABIN7868215

The Rabbit Polyclonal anti-PEG3 antibody (ABIN7868215) specifically detects PEG3 in WB, ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for PEG3 antibody (AA 1-1548) (ABIN7868215)

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PEG3 Antibody

Binding Specificity: AA 1-1548

Purpose: PEG3 Antibody / Paternally-expressed gene 3

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids M1-R1548) was used as the immunogen for the PEG3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PEG3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PEG3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3

Background: Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene. In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

UniProt: Q9GZU2