SPAG7 antibody (AA 1-199)

Catalog No. ABIN7868361

The Rabbit Polyclonal anti-SPAG7 antibody is suitable to detect SPAG7 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, FACS, IF and IHC (p).

Quick Overview for SPAG7 antibody (AA 1-199) (ABIN7868361)

Target: SPAG7 (Sperm Associated Antigen 7 (SPAG7))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SPAG7 Antibody

Binding Specificity: AA 1-199

Purpose: SPAG7 Antibody / Sperm-associated antigen 7

Purification: Antigen affinity purified

Immunogen: Amino acids M1-D199 from the human protein were used as the immunogen for the SPAG7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SPAG7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SPAG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SPAG7

Target: SPAG7 (Sperm Associated Antigen 7 (SPAG7))

Alternative Name: SPAG7

Background: SPAG7 (Sperm-associated antigen 7) is a cytoplasmic RNA-binding protein that plays a role in RNA processing and transport. While initially identified in the context of reproductive biology, SPAG7 is expressed in a range of tissues and is thought to participate in the regulation of RNA metabolism, including splicing and ribonucleoprotein complex formation. A SPAG7 antibody is frequently used in studies of RNA regulation, germ cell biology, and post-transcriptional gene control.

SPAG7 is localized to the cytoplasm and has been associated with RNA-binding activity that influences the stability and localization of specific transcripts. This suggests an important role in coordinating gene expression at the post-transcriptional level. Employing a SPAG7 antibody enables researchers to examine its subcellular distribution and assess its contribution to RNA-based regulatory pathways.

Although initially discovered in sperm, SPAG7 has broader biological functions beyond reproductive processes. It has been reported to interact with nuclear pore and ribonucleoprotein-associated proteins, supporting its involvement in RNA export and turnover. Altered SPAG7 expression patterns have been observed in certain pathological contexts, including cancer, where RNA regulation is frequently disrupted. Using a SPAG7 antibody provides a valuable tool to explore these potential disease associations and clarify its functional significance.

NSJ Bioreagents offers a high-quality SPAG7 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Choosing a SPAG7 antibody from NSJ Bioreagents ensures consistent performance and reliable detection in studies of RNA processing, germ cell function, and molecular regulation.

UniProt: O75391