CD57 antibody (AA 1-200)

Catalog No. ABIN7868391

The Mouse Monoclonal anti-CD57 antibody is suitable to detect CD57 in samples from Human. It has been validated for IHC (p).

Quick Overview for CD57 antibody (AA 1-200) (ABIN7868391)

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD57 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: NK1-7565

Product Details anti-CD57 Antibody

Binding Specificity: AA 1-200

Purpose: CD57 Antibody / HNK-1

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 1-200) from the human protein was used as the immunogen for the CD57 antibody.

Isotype: IgG2, lambda

Application Details

Application Notes: Optimal dilution of the CD57 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD57 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Alternative Name: CD57

Background: Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

UniProt: Q9P2W7

Pathways: Glycosaminoglycan Metabolic Process