Hexokinase 1 antibody (AA 1-200)

Catalog No. ABIN7868523

The Mouse Monoclonal anti-Hexokinase 1 antibody is suitable to detect Hexokinase 1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Hexokinase 1 antibody (AA 1-200) (ABIN7868523)

Target: Hexokinase 1 (HK1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hexokinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HK1-9506

Product Details anti-Hexokinase 1 Antibody

Binding Specificity: AA 1-200

Purpose: HK1 Antibody / Hexokinase 1

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-200 from human Hexokinase 1 protein was used as the immunogen for the HK1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the HK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Hexokinase 1

Target: Hexokinase 1 (HK1)

Alternative Name: HK1

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

UniProt: P19367

Pathways: Carbohydrate Homeostasis, Warburg Effect