Hexokinase 1 antibody (AA 1-200)

Catalog No. ABIN7868528

This Mouse Monoclonal antibody specifically detects Hexokinase 1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Hexokinase 1 antibody (AA 1-200) (ABIN7868528)

Target: Hexokinase 1 (HK1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hexokinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: HK1-9504

Product Details anti-Hexokinase 1 Antibody

Binding Specificity: AA 1-200

Purpose: Hexokinase 1 Antibody / HK1 (azide and preservative free)

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-200 from human HK1 protein was used as the immunogen for the Hexokinase 1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Hexokinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Hexokinase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Hexokinase 1

Target: Hexokinase 1 (HK1)

Alternative Name: Hexokinase 1

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

UniProt: P19367

Pathways: Carbohydrate Homeostasis, Warburg Effect