Recombinant VEGF antibody (AA 1-200)

Catalog No. ABIN7868792

This Rabbit Monoclonal antibody specifically detects VEGF in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant VEGF antibody (AA 1-200) (ABIN7868792)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This VEGF antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: VEGFA-7758R

Product Details anti-VEGF Antibody

Binding Specificity: AA 1-200

Purpose: Vascular Endothelial Growth Factor Antibody / VEGF (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Vascular Endothelial Growth Factor antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Vascular Endothelial Growth Factor antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Vascular Endothelial Growth Factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: Vascular Endothelial Growth Factor

Background: This mAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

UniProt: P15692