GRB14 antibody (AA 1-246)

Catalog No. ABIN7868919

The Rabbit Polyclonal anti-GRB14 antibody is suitable to detect GRB14 in samples from Human. It has been validated for ELISA, WB, IF, IHC (p) and FACS.

Quick Overview for GRB14 antibody (AA 1-246) (ABIN7868919)

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRB14 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-GRB14 Antibody

Binding Specificity: AA 1-246

Purpose: GRB14 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-Q246) was used as the immunogen for the GRB14 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GRB14 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GRB14 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GRB14

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Alternative Name: GRB14

Background: Growth factor receptor-bound protein 14 is a protein that in humans is encoded by the GRB14 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

UniProt: Q14449