SCD antibody (AA 1-250)

Catalog No. ABIN7868950

The Mouse Monoclonal anti-SCD antibody (Clone SDC1-7183) (ABIN7868950) specifically detects SCD in IHC (p). The antibody is reactive with Human samples.

Quick Overview for SCD antibody (AA 1-250) (ABIN7868950)

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SCD antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SDC1-7183

Product Details anti-SCD Antibody

Binding Specificity: AA 1-250

Purpose: SCD1 Antibody / Syndecan-1 / CD138

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-250) from the human protein was used as the immunogen for the SCD1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the SCD1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SCD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SCD

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Alternative Name: SCD1

Background: CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinomas.

UniProt: P18827

Pathways: Brown Fat Cell Differentiation