HAX1 antibody (AA 1-279)

Catalog No. ABIN7869041

This Rabbit Polyclonal antibody specifically detects HAX1 in WB, ELISA, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for HAX1 antibody (AA 1-279) (ABIN7869041)

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-HAX1 Antibody

Binding Specificity: AA 1-279

Purpose: HAX1 Antibody / HCLS1-associated protein X-1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-R279) was used as the immunogen for the HAX1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HAX1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HAX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Alternative Name: HAX1

Background: HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization