PTF1A antibody (AA 1-292)

Catalog No. ABIN7869061

The Rabbit Polyclonal anti-PTF1A antibody (ABIN7869061) specifically detects PTF1A in WB, ELISA, IF and FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PTF1A antibody (AA 1-292) (ABIN7869061)

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTF1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PTF1A Antibody

Binding Specificity: AA 1-292

Purpose: PTF1A Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-Q292) was used as the immunogen for the PTF1A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PTF1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PTF1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Alternative Name: PTF1A

Background: Pancreas transcription factor 1 subunit alpha is a protein that in humans is encoded by the PTF1A gene. It is mapped to 10p12.2. This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway