Exonuclease 1 antibody (AA 1-294)

Catalog No. ABIN7869064

The Rabbit Polyclonal anti-Exonuclease 1 antibody (ABIN7869064) specifically detects Exonuclease 1 in WB, ELISA, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Exonuclease 1 antibody (AA 1-294) (ABIN7869064)

Target: Exonuclease 1 (EXO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Exonuclease 1 Antibody

Binding Specificity: AA 1-294

Purpose: Exonuclease 1 Antibody / EXO1

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids M1-K294) was used as the immunogen for the Exonuclease 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Exonuclease 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Exonuclease 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: Exonuclease 1

Background: Exonuclease 1 is an enzyme that in humans is encoded by the EXO1 gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

UniProt: Q9UQ84

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response