Kallikrein 6 antibody (AA 1-30)
Quick Overview for Kallikrein 6 antibody (AA 1-30) (ABIN7869094)
Target
See all Kallikrein 6 (KLK6) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-30
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Purpose
- KLK6 Antibody / Kallikrein 6
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Purification
- Purified
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Immunogen
- A portion of amino acids 1-30 from the human protein was used as the immunogen for the KLK6 antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the KLK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the KLK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Kallikrein 6 (KLK6)
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Alternative Name
- KLK6
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Background
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
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UniProt
- Q92876
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Pathways
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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