PRMT1 antibody (AA 1-311)

Catalog No. ABIN7869179

This Rabbit Polyclonal antibody specifically detects PRMT1 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRMT1 antibody (AA 1-311) (ABIN7869179)

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PRMT1 Antibody

Binding Specificity: AA 1-311

Purpose: HRMT1L2 Antibody / PRMT1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-H311) was used as the immunogen for the HRMT1L2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HRMT1L2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HRMT1L2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRMT1

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Alternative Name: HRMT1L2

Background: Protein arginine N-methyltransferase 1, also called Heterogeneous nuclear ribonucleoprotein methyltransferase 1 like 2 (HRMT1L2) is an enzyme that in humans is encoded by the PRMT1 gene. It is mapped to 19q13.33. This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

UniProt: Q99873