GATA4 antibody (AA 1-332)

Catalog No. ABIN7869201

The Rabbit Polyclonal anti-GATA4 antibody is suitable to detect GATA4 in samples from Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for GATA4 antibody (AA 1-332) (ABIN7869201)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GATA4 Antibody

Binding Specificity: AA 1-332

Purpose: Zebrafish Gata4 Antibody / GATA-binding factor 4

Purification: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Gata4 recombinant protein (amino acids M1-M332) was used as the immunogen for the Zebrafish Gata4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Gata4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Gata4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Alternative Name: Gata4

Background: GATA-binding factor 4 (Gata4) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell differentiation. In zebrafish (Danio rerio), Gata4 plays a critical role in the development of the heart, endoderm, and gastrointestinal tract, mirroring its conserved function in vertebrate organogenesis.

Gata4 is expressed early during zebrafish embryogenesis, particularly in the cardiac mesoderm and endodermal precursors. It functions as a key regulator of cardiomyocyte differentiation, heart tube formation, and gut development. Gata4 also interacts with other transcription factors such as Nkx2.5 and Tbx5 to coordinate cardiac gene expression programs.

Due to its essential role in heart development and its evolutionary conservation, zebrafish Gata4 is widely studied in models of congenital heart disease, organ specification, and regenerative biology. It serves as a valuable molecular marker and research target for developmental biology, gene regulation, and disease modeling.

UniProt: Q09JY7

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis