GHITM antibody (AA 1-345)

Catalog No. ABIN7869226

The Rabbit Polyclonal anti-GHITM antibody (ABIN7869226) specifically detects GHITM in ELISA, WB, IF, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GHITM antibody (AA 1-345) (ABIN7869226)

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHITM antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GHITM Antibody

Binding Specificity: AA 1-345

Purpose: GHITM Antibody / MICS1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-K345) was used as the immunogen for the GHITM antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GHITM antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GHITM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GHITM

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Alternative Name: GHITM

Background: Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 or DERP2, is a mitochondrial protein which localizes in the inner membrane. GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.

UniProt: Q9H3K2

Pathways: SARS-CoV-2 Protein Interactome