The Rabbit Polyclonal anti-Mesp2 antibody (ABIN7869298) specifically detects Mesp2 in ELISA, WB, IF, FACS and IHC (p).
The antibody is reactive with Human samples.
Mesp2
Reactivity: Human
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the MESP2 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the MESP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
Mesp2
(Mesoderm Posterior 2 Homolog (Mesp2))
Alternative Name
MESP2
Background
Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene. This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).