The Rabbit Polyclonal anti-Cnpase antibody (ABIN7869340) specifically detects Cnpase in WB, ELISA, FACS, IF and IHC (p).
The antibody is reactive with Human, Mouse and Rat samples.
CNP
Reactivity: Human, Mouse, Rat
WB, IHC, ELISA, FACS, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the CNP antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the CNP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
2',3'-Cyclic-nucleotide 3'-phosphodiesterase, also known as CNPase, is an enzyme that in humans is encoded by the CNP gene. And this gene is mapped to 17q21.2. CNPase is named for its ability to catalyze the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. CNPase is thought to play a critical role in the events leading up to myelination. Additionally, CNPase has been demonstrated to inhibit the replication of HIV-1 and other primate lentiviruses by binding the retroviral Gag protein and inhibiting the genesis of nascent viral particles.